anti-PDE6A antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG10806
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PDE6A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | Confocal, Dot, ELISA, ICC/IF, IHC, IP, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PDE6A |
| 抗原物种 | Human |
| 抗原 | Synthetic cyclic peptide common to all PDE6 alpha variants. |
| 偶联标记 | Un-conjugated |
| 別名 | RP43; CGPR-A; PDEA; GMP-PDE alpha; PDE V-B1; EC 3.1.4.35; Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha |
应用说明
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P16499 Human Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha |
|---|---|
| 基因名称 | PDE6A |
| 全名 | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| 背景介绍 | This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. [provided by RefSeq, Jul 2008] |
| 生物功能 | This protein participates in processes of transmission and amplification of the visual signal. [UniProt] |
| 预测分子量 | 100 kDa |
检测图片 (1)
ARG10806 anti-PDE6A antibody IHC image
Immunohistochemistry: Lung tissue stained with ARG10806 anti-PDE6A antibody.
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