anti-PDE7A antibody
CAT.NO. : ARG10807
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PDE7A |
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反应物种 | Hu, Ms, Rat |
应用 | Dot, ELISA, IHC-P, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PDE7A |
抗原物种 | Human |
抗原 | Synthetic cyclic peptide common to all PDE7A variants. |
偶联标记 | Un-conjugated |
別名 | PDE7; High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; EC 3.1.4.53; TM22; HCP1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | Tris-Glycine Buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 30% Glycerol and 0.5% BSA |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P70453 Mouse High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A Swiss-port # Q13946 Human High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A |
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基因名称 | PDE7A |
全名 | phosphodiesterase 7A |
背景介绍 | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011] |
生物功能 | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. [UniProt] |
预测分子量 | 56 kDa |
检测图片 (3)
ARG10807 anti-PDE7A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human ovarian medulla tissue stained with ARG10807 anti-PDE7A antibody at 1:200 dilution.
ARG10807 anti-PDE7A antibody WB image
Western blot: 1) SKNMBE, 2) MCF7, 3) Human testis, and 4) Rat testis stained with ARG10807 anti-PDE7A antibody.
ARG10807 anti-PDE7A antibody WB image
Western blot: 1) Lung, 2) Kidney, 3) Testis, 4) Pancreas, 5&7) Heart, and 6) Brain lysates stained with ARG10807 anti-PDE7A antibody at 1:500 dilution.
