anti-PDIA2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PDIA2
  • 反应物种: Hu, Ms, Rat
  • 应用: FACS, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PDIA2
  • 抗原物种: Human
  • 抗原: Synthetic peptide derived from Human PDIA2.
  • Brand:
CAT.NO. : ARG42762
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PDIA2
反应物种Hu, Ms, Rat
应用FACS, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PDIA2
抗原物种Human
抗原Synthetic peptide derived from Human PDIA2.
偶联标记Un-conjugated
別名PDA2; Pancreas-specific protein disulfide isomerase; PDIR; PDIP; PDI; Protein disulfide-isomerase A2; PDIp; EC 5.3.4.1
应用说明
应用建议
应用推荐稀释比
FACS1:50
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HeLa
实际分子量~ 70 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 64714 Human PDIA2

GeneID: 69191 Mouse PDIA2

Swiss-port # D3Z6P0 Mouse Protein disulfide-isomerase A2

Swiss-port # Q13087 Human Protein disulfide-isomerase A2

基因名称PDIA2
全名protein disulfide isomerase family A, member 2
背景介绍This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, two TRX-like domains and a C-terminal ER-retention sequence. The protein plays a role in the folding of nascent proteins in the endoplasmic reticulum by forming disulfide bonds through its thiol isomerase, oxidase, and reductase activity. The encoded protein also possesses estradiol-binding activity and can modulate intracellular estradiol levels. [provided by RefSeq, Sep 2017]
生物功能Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. [UniProt]
细胞定位Endoplasmic reticulum lumen. [UniProt]
预测分子量58 kDa
翻译后修饰The disulfide-linked homodimer exhibits an enhanced chaperone activity.

Glycosylated. [UniProt]
检测图片 (1)
  • ARG42762 anti-PDIA2 antibody WB image

    Western blot: HeLa cell lysate stained with ARG42762 anti-PDIA2 antibody.

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