anti-PGAM1 + 2 + 4 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG63456
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes PGAM1 + 2 + 4 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Pig |
| 预测物种 | Cow, Dog |
| 应用 | WB |
| 特异性 | Please note this antibody is expected to recognize the products of 3 highly similar genes. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PGAM1 + 2 + 4 |
| 抗原 | C-KAMEAVAAQGKAKK |
| 偶联标记 | Un-conjugated |
| 別名 | PGAMA; EC 3.1.3.13; Phosphoglycerate mutase isozyme B; HEL-S-35; EC 5.4.2.11; PGAM-B; BPG-dependent PGAM 1; Phosphoglycerate mutase 1; EC 5.4.2.4 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PGAM1 |
| 全名 | phosphoglycerate mutase 1 (brain) |
| 背景介绍 | Phosphoglyceric acid mutase (EC 2.7.5.3) is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 [PubMed 4811757]).[supplied by OMIM, Nov 2010] |
| 生物功能 | Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. [UniProt] |
| 研究领域 | Cancer antibody; Metabolism antibody; Signaling Transduction antibody |
| 预测分子量 | 29 kDa |
| 翻译后修饰 | Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme. |
检测图片 (2)
ARG63456 anti-PGAM1 + 2 + 4 antibody WB image
Western blot: Human liver lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63456 anti-PGAM1 + 2 + 4 antibody at 0.01 µg/ml dilution.
ARG63456 anti-PGAM1 + 2 + 4 antibody WB image
Western blot: 35 µg of Human (A), Mouse (B), Rat (C) and Pig (D) liver lysates (in RIPA buffer) stained with ARG63456 anti-PGAM1 + 2 + 4 antibody at 0.05 µg/ml dilution and incubated at RT for 1 hour.
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