anti-PGK1 antibody [2F4]

CAT.NO. : ARG57152

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [2F4] recognizes PGK1
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	2F4
同位型	IgG1, kappa
靶点名称	PGK1
抗原物种	Human
抗原	Recombinant fragment around aa. 1-417 of Human PGK1
偶联标记	Un-conjugated
別名	EC 2.7.2.3; Primer recognition protein 2; PGKA; PRP 2; Phosphoglycerate kinase 1; MIG10; Cell migration-inducing gene 10 protein; HEL-S-68p

应用说明

应用建议

应用	推荐稀释比
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 5230 Human PGK1 Swiss-port # P00558 Human Phosphoglycerate kinase 1
基因名称	PGK1
全名	phosphoglycerate kinase 1
背景介绍	The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014]
生物功能	In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). [UniProt]
预测分子量	45 kDa

检测图片 (1)

ARG57152 anti-PGK1 antibody [2F4] WB image
Western blot: 40 µg of 1) HeLa, 2) LNCaP, 3) A549, 4) HepG2, 5) 293T, 6) K562, and 7) Jurkat cell lysates stained with ARG57152 anti-PGK1 antibody [2F4] at 1:1000.

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