anti-PGM1 antibody [84G2]
![anti-PGM1 antibody [84G2]](/upload/image/products/ARG57065_WB_1_210_205.jpg)
![anti-PGM1 antibody [84G2]](/upload/image/products/ARG57065_WB_1.jpg)
Key features and details
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- 克隆:
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- 靶点名称:
- 抗原物种:
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CAT.NO. : ARG57065
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [84G2] recognizes PGM1 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 84G2 |
| 同位型 | IgG1, kappa |
| 靶点名称 | PGM1 |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-562 of Human PGM1. |
| 偶联标记 | Un-conjugated |
| 別名 | CDG1T; Phosphoglucomutase-1; GSD14; EC 5.4.2.2; Glucose phosphomutase 1; PGM 1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PGM1 |
| 全名 | phosphoglucomutase 1 |
| 背景介绍 | The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010] |
| 生物功能 | This enzyme participates in both the breakdown and synthesis of glucose. [UniProt] |
| 预测分子量 | 61 kDa |
| 翻译后修饰 | Phosphorylation at Thr-467 by PAK1 significantly enhances enzymatic activity. |
检测图片 (1)
ARG57065 anti-PGM1 antibody [84G2] WB image
Western blot: 40 µg of 1) 293T cell lysate, 2) HepG2 cell lysate, 3) NIH/3T3 cell lysate, 4) Jurkat cell lysate, 5) HeLa cell lysate, 6) U87MG cell lysate stained with ARG57065 anti-PGM1 antibody [84G2] at 1:1000.
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