anti-PHOX2B antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PHOX2B
  • 反应物种: Hu, Ms
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PHOX2B
  • 抗原物种: Human
  • 抗原: Synthetic peptide of Human PHOX2B.
  • Brand:
CAT.NO. : ARG41552
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PHOX2B
反应物种Hu, Ms
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PHOX2B
抗原物种Human
抗原Synthetic peptide of Human PHOX2B.
偶联标记Un-conjugated
別名NBPhox; PHOX2B homeodomain protein; Paired-like homeobox 2B; Neuroblastoma Phox; Paired mesoderm homeobox protein 2B; PMX2B; NBLST2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:100 - 1:500
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Neuro-2a
实际分子量~ 35 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 18935 Mouse PHOX2B

GeneID: 8929 Human PHOX2B

Swiss-port # O35690 Mouse Paired mesoderm homeobox protein 2B

Swiss-port # Q99453 Human Paired mesoderm homeobox protein 2B

基因名称PHOX2B
全名paired-like homeobox 2b
背景介绍The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq, Jul 2008]
生物功能Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element. [UniProt]
细胞定位Nucleus. [UniProt]
预测分子量32 kDa
检测图片 (1)
  • ARG41552 anti-PHOX2B antibody WB image

    Western blot: Neuro-2a cell lysate stained with ARG41552 anti-PHOX2B antibody.

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