anti-PIK3R5 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44471
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PIK3R5 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PIK3R5 |
| 抗原物种 | Human |
| 抗原 | Human PIK3R5 recombinant protein |
| 偶联标记 | Un-conjugated |
| 別名 | PIK3R5; Phosphoinositide-3-Kinase Regulatory Subunit 5; P101-PI3K; P101; Phosphatidylinositol 4,5-Bisphosphate 3-Kinase Regulatory Subunit; Phosphoinositide 3-Kinase Regulatory Subunit 5; PI3-Kinase P101 Subunit; PtdIns-3-Kinase P101; Protein FOAP-2; Phosphoinositide-3-Kinase, Regulatory Subunit 5; PtdIns-3-Kinase Regulatory Subunit; PI3-Kinase Regulatory Subunit 5 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|
| 应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
| 抗菌剂 | 0.05% Sodium azide |
| 稳定剂 | 4% Trehalose |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | Swiss-port # Q5SW28 Mouse Phosphoinositide 3-kinase regulatory subunit 5 Swiss-port # Q8WYR1 Human Phosphoinositide 3-kinase regulatory subunit 5 |
|---|---|
| 基因名称 | PIK3R5 |
| 全名 | Phosphoinositide-3-Kinase Regulatory Subunit 5 |
| 背景介绍 | Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. |
| 生物功能 | Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG. |
| 细胞定位 | Cell membrane, Cytoplasm, Membrane, Nucleus |
| 预测分子量 | 97 kDa |
| 翻译后修饰 | Acetylation, Phosphoprotein |
检测图片 (4)
ARG44471 anti-PIK3R5 antibody WB image
Western blot: Jurkat and K562 stained with ARG44471 anti-PIK3R5 antibody at 0.5 μg/mL dilution.
ARG44471 anti-PIK3R5 antibody FACS image
Flow Cytometry: JK stained with ARG44471 anti-PIK3R5 antibody at 1 μg/10^6 cells dilution.
ARG44471 anti-PIK3R5 antibody WB image
Western blot: C6 stained with ARG44471 anti-PIK3R5 antibody at 0.5 μg/mL dilution.
ARG44471 anti-PIK3R5 antibody WB image
Western blot: Mouse brain and Neuro-2a stained with ARG44471 anti-PIK3R5 antibody at 0.5 μg/mL dilution.
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