anti-Pirin antibody
产品描述 | Rabbit Polyclonal antibody recognizes Pirin |
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反应物种 | Hu, Ms, Rat, Mk |
应用 | FACS, ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | Pirin |
抗原物种 | Human |
抗原 | Human Pirin recombinant protein |
偶联标记 | Un-conjugated |
別名 | PIR; Pirin; Probable Quercetin 2,3-Dioxygenase PIR; Pirin (Iron-Binding Nuclear Protein); Probable Quercetinase |
应用建议 |
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应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
数据库连接 | |
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基因名称 | PIR |
全名 | Pirin |
背景介绍 | This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. |
生物功能 | Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity. |
细胞定位 | Cytoplasm, Nucleus |
预测分子量 | 32 kDa |
ARG44472 anti-Pirin antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44472 anti-Pirin antibody at 5 μg/mL dilution.
ARG44472 anti-Pirin antibody WB image
Western blot: HepG2 and HeLa stained with ARG44472 anti-Pirin antibody at 0.5 μg/mL dilution.
ARG44472 anti-Pirin antibody FACS image
Flow Cytometry: HepG2 stained with ARG44472 anti-Pirin antibody at 1 μg/10^6 cells dilution.
ARG44472 anti-Pirin antibody WB image
Western blot: RH-35 stained with ARG44472 anti-Pirin antibody at 0.5 μg/mL dilution.
ARG44472 anti-Pirin antibody WB image
Western blot: NIH/3T3 stained with ARG44472 anti-Pirin antibody at 0.5 μg/mL dilution.
ARG44472 anti-Pirin antibody WB image
Western blot: COS-7 stained with ARG44472 anti-Pirin antibodyat 0.5 μg/mL dilution.
