anti-PKLR antibody [1E3]

CAT.NO. : ARG56998

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1E3] recognizes PKLR
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	1E3
同位型	IgG1, kappa
靶点名称	PKLR
抗原物种	Human
抗原	Recombinant fragment around aa. 47-574 of Human PKLR.
偶联标记	Un-conjugated
別名	PKR; PKRL; PK1; Pyruvate kinase isozymes L/R; R-type/L-type pyruvate kinase; Pyruvate kinase PKLR; Pyruvate kinase 1; EC 2.7.1.40; RPK; Red cell/liver pyruvate kinase; PKL

应用说明

应用建议

应用	推荐稀释比
WB	1:500

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 5313 Human PKLR Swiss-port # P30613 Human Pyruvate kinase PKLR
基因名称	PKLR
全名	pyruvate kinase, liver and RBC
背景介绍	The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
生物功能	Plays a key role in glycolysis. [UniProt]
预测分子量	62 kDa

检测图片 (2)

ARG56998 anti-PKLR antibody [1E3] WB image
Western blot: 40 µg of 293T cell lysate stained with ARG56998 anti-PKLR antibody [1E3] at 1:500.
ARG56998 anti-PKLR antibody [1E3] WB image
Western blot: 40 µg of 1) Balb-3T3 cell lysate, 2) HeLa cell lysate, 3) Raji cell lysate, 4) K562 cell lysate, 5) A549 cell lysate. stained with ARG56998 anti-PKLR antibody [1E3] at 1:500.

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