anti-PNPLA3 / Adiponutrin antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG66868
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PNPLA3 / Adiponutrin |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PNPLA3 / Adiponutrin |
| 抗原物种 | Human |
| 抗原 | Recombinant full-length protein of Human PNPLA3 / Adiponutrin. |
| 偶联标记 | Un-conjugated |
| 別名 | ADPN; Calcium-independent phospholipase A2-epsilon; iPLA(2)epsilon; Adiponutrin; Patatin-like phospholipase domain-containing protein 3; iPLA2-epsilon; EC 2.3.1.-; C22orf20; EC 3.1.1.3; Acylglycerol O-acyltransferase |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 实际分子量 | ~ 110 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q91WW7 Mouse Patatin-like phospholipase domain-containing protein 3 Swiss-port # Q9NST1 Human Patatin-like phospholipase domain-containing protein 3 |
|---|---|
| 基因名称 | PNPLA3 |
| 全名 | patatin-like phospholipase domain containing 3 |
| 背景介绍 | The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes. [provided by RefSeq, Jul 2008] |
| 生物功能 | Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA (PubMed:22560221). Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides (PubMed:15364929, PubMed:20034933, PubMed:22560221). [UniProt] |
| 细胞定位 | Membrane; Single-pass type II membrane protein. [UniProt] |
| 预测分子量 | 53 kDa |
检测图片 (2)
ARG66868 anti-PNPLA3 / Adiponutrin antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human kidney tissue. Antigen Retrieval: Heat mediation was performed in Sodium citrate buffer (pH 6.0). The section was stained with ARG66868 anti-PNPLA3 / Adiponutrin antibody at room temperature.
ARG66868 anti-PNPLA3 / Adiponutrin antibody WB image
Western blot: HeLa and Mouse testis lysates stained with ARG66868 anti-PNPLA3 / Adiponutrin antibody.
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