anti-Podoplanin antibody [56F7]

CAT.NO. : ARG57071

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [56F7] recognizes Podoplanin
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	56F7
同位型	IgG1, kappa
靶点名称	Podoplanin
抗原物种	Human
抗原	Recombinant fragment around aa. 99-207 of Human Podoplanin.
偶联标记	Un-conjugated
別名	PDPN; T1A2; T1A; GP36; Aggrus; Gp38; T1A-2; Glycoprotein 36; PA2.26 antigen; TI1A; AGGRUS; HT1A-1; OTS8; Gp36; PA2.26; T1-alpha; Podoplanin; GP40

应用说明

应用建议

应用	推荐稀释比
WB	Assay-dependent

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 10630 Human PDPN Swiss-port # Q86YL7 Human Podoplanin
基因名称	PDPN
全名	podoplanin
背景介绍	This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
生物功能	May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels. [UniProt]
预测分子量	17 kDa
翻译后修饰	Extensively O-glycosylated. Contains sialic acid residues. O-glycosylation is necessary for platelet aggregation activity. The N-terminus is blocked. [UniProt]

检测图片 (1)

ARG57071 anti-Podoplanin antibody [56F7] WB image
Western blot: 40 µg of HeLa cell lysates stained with ARG57071 anti-Podoplanin antibody [56F7] at 1:1000.

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