anti-POLR1C antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes POLR1C
  • 反应物种: Hu
  • 应用: ELISA, FACS, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: POLR1C
  • 抗原物种: Human
  • 抗原: Human POLR1C recombinant protein
  • Brand:
CAT.NO. : ARG43924
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes POLR1C
反应物种Hu
应用ELISA, FACS, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称POLR1C
抗原物种Human
抗原Human POLR1C recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameDNA-directed RNA polymerases I and III subunit RPAC1
別名POLR1C; RNA Polymerase I And III Subunit C; RPA40; RPA39; RPC40; AC40; RPAC1; RPA5; DNA-Directed RNA Polymerases I And III 40 KDa Polypeptide; DNA-Directed RNA Polymerases I And III Subunit RPAC1; Polymerase (RNA) I Polypeptide C, 30kDa; DNA-Directed RNA Polymerase I Subunit C; RNA Polymerases I And III Subunit AC1; RNA Polymerase I Subunit C; Polymerase (RNA) I Subunit C; POLR1E; HLD11; TC
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
FACS1-3 µg/1x10^6 cells
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 9533 Human POLR1C

Swiss-port # O15160 Human DNA-directed RNA polymerases I and III subunit RPAC1

基因名称POLR1C
全名RNA Polymerase I And III Subunit C
背景介绍The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.
生物功能DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
细胞定位DNA-directed RNA polymerase, Nucleus
预测分子量39 kDa
翻译后修饰Acetylation, Phosphoprotein
检测图片 (2)
  • ARG43924 anti-POLR1C antibody WB image

    Western blot: 293T, K562 and RT4 stained withARG43924 anti-POLR1C antibody at 0.5 μg/mL dilution.

  • ARG43924 anti-POLR1C antibody FACS image

    Flow Cytometry: RT4 cells stained withARG43924anti-POLR1C antibody (blue) at 1 μg/1x10^6 cells dilution.

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