anti-POLR1C antibody
CAT.NO. : ARG43924
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes POLR1C |
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反应物种 | Hu |
应用 | ELISA, FACS, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | POLR1C |
抗原物种 | Human |
抗原 | Human POLR1C recombinant protein |
表达系统 | E.coli |
偶联标记 | Un-conjugated |
Protein Full name | DNA-directed RNA polymerases I and III subunit RPAC1 |
別名 | POLR1C; RNA Polymerase I And III Subunit C; RPA40; RPA39; RPC40; AC40; RPAC1; RPA5; DNA-Directed RNA Polymerases I And III 40 KDa Polypeptide; DNA-Directed RNA Polymerases I And III Subunit RPAC1; Polymerase (RNA) I Polypeptide C, 30kDa; DNA-Directed RNA Polymerase I Subunit C; RNA Polymerases I And III Subunit AC1; RNA Polymerase I Subunit C; Polymerase (RNA) I Subunit C; POLR1E; HLD11; TC |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # O15160 Human DNA-directed RNA polymerases I and III subunit RPAC1 |
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基因名称 | POLR1C |
全名 | RNA Polymerase I And III Subunit C |
背景介绍 | The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants. |
生物功能 | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft. |
细胞定位 | DNA-directed RNA polymerase, Nucleus |
预测分子量 | 39 kDa |
翻译后修饰 | Acetylation, Phosphoprotein |
