anti-PON2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes PON2
  • 反应物种: Hu
  • 预测物种: Dog, Rat, Pig
  • 应用: IHC-P, WB
  • 特异性: This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PON2
  • Brand:
CAT.NO. : ARG65208
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes PON2
反应物种Hu
预测物种Dog, Rat, Pig
应用IHC-P, WB
特异性This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称PON2
抗原物种Human
抗原C-EKPRARELRIS
偶联标记Un-conjugated
別名Aromatic esterase 2; EC 3.1.1.81; A-esterase 2; Serum paraoxonase/arylesterase 2; Serum aryldialkylphosphatase 2; PON 2; EC 3.1.1.2
应用说明
应用建议
应用推荐稀释比
IHC-P3 - 5 µg/ml
WB0.2 - 0.6 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5445 Human PON2

Swiss-port # Q15165 Human Serum paraoxonase/arylesterase 2

背景介绍This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
研究领域Cell Biology and Cellular Response antibody; Metabolism antibody; Neuroscience antibody; Signaling Transduction antibody
预测分子量39 kDa
翻译后修饰The signal sequence is not cleaved.
检测图片 (2)
  • ARG65208 anti-PON2 antibody WB image

    Western Blot: HepG2 lysate (35 µg protein in RIPA buffer) stained with ARG65208 anti-PON2 antibody at 0.2 µg/ml dilution.

  • ARG65208 anti-PON2 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human placenta tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG65208 anti-PON2 antibody at 3.75 µg/ml dilution followed by AP-staining.

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