anti-POU3F1 / OCT6 antibody
CAT.NO. : ARG44894
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概述
产品描述 | Mouse Monoclonal antibody recognizes POU3F1 / OCT6 |
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反应物种 | Ms, Rat |
应用 | IHC-P, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | POU3F1 / OCT6 |
抗原物种 | Mouse |
偶联标记 | Un-conjugated |
別名 | POU3F1; POU Class 3 Homeobox 1; OCT6; SCIP; OTF6; POU Domain, Class 3, Transcription Factor 1; Octamer-Binding Transcription Factor 6; POU Domain Transcription Factor SCIP; Octamer-Binding Protein 6; OTF-6; POU Domain Class 3, Transcription Factor 1; Oct-6 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
抗菌剂 | 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # P20267 Rat POU domain, class 3, transcription factor 1 Swiss-port # P21952 Mouse POU domain, class 3, transcription factor 1 |
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基因名称 | POU3F1 |
全名 | POU Class 3 Homeobox 1 |
背景介绍 | Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of gene expression; and positive regulation of transcription, DNA-templated. Predicted to act upstream of or within keratinocyte differentiation; nervous system development; and positive regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022] |
生物功能 | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters. Acts as a transcriptional repressor of myelin-specific genes. [Uniprot] |
细胞定位 | Nucleus. [Uniprot] |
预测分子量 | 45 kDa |
