anti-PPP2R2A antibody
CAT.NO. : ARG56218
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PPP2R2A |
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反应物种 | Hu |
预测物种 | Ms, Rat, Mk, Pig, Rb |
应用 | ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PPP2R2A |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 43-71 (N-terminus) of Human PPP2R2A. |
偶联标记 | Un-conjugated |
別名 | PR55A; B55A; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; PP2A subunit B isoform B55-alpha; PR52A; PP2A subunit B isoform R2-alpha; PP2A subunit B isoform alpha; B55ALPHA; PP2A subunit B isoform PR55-alpha |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
阳性对照 | ZR-75-1 |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
抗菌剂 | 0.09% (W/V) Sodium azide. |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P63151 Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha |
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基因名称 | PPP2R2A |
全名 | protein phosphatase 2, regulatory subunit B, alpha |
背景介绍 | The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010] |
生物功能 | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. [UniProt] |
预测分子量 | 52 kDa |
检测图片 (3)
ARG56218 anti-PPP2R2A antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG56218 anti-PPP2R2A antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
ARG56218 anti-PPP2R2A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human liver tissue stained with ARG56218 anti-PPP2R2A antibody at 1:25 dilution.
ARG56218 anti-PPP2R2A antibody WB image
Western blot: 35 µg of ZR-75-1 cell lysate stained with ARG56218 anti-PPP2R2A antibody.
