anti-PPP2R3B antibody
CAT.NO. : ARG40237
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PPP2R3B |
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反应物种 | Hu, Ms |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PPP2R3B |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 356-575 of Human PPP2R3B (NP_037371.2). |
偶联标记 | Un-conjugated |
別名 | PPP2R3L; PR48; PPP2R3LY; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta; Protein phosphatase 2A 48 kDa regulatory subunit; NYREN8; PP2A subunit B isoform PR48 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | SKOV3 and SW620 | ||||
实际分子量 | ~ 70 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q9Y5P8 Human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit bet |
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基因名称 | PPP2R3B |
全名 | protein phosphatase 2, regulatory subunit B'', beta |
背景介绍 | Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. [provided by RefSeq, Apr 2010] |
生物功能 | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. [UniProt] |
细胞定位 | Nucleus. [UniProt] |
预测分子量 | 65 kDa |
