anti-PRDM14 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG56309
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRDM14 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ChIP, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRDM14 |
| 抗原物种 | Human |
| 抗原 | Recombinant protein of Human PRDM14 |
| 偶联标记 | Un-conjugated |
| 別名 | PFM11; PR domain zinc finger protein 14; PR domain-containing protein 14; EC 2.1.1.- |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HeLa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRDM14 |
| 全名 | PR domain containing 14 |
| 背景介绍 | This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011] |
| 生物功能 | Transcription factor that has both positive and negative roles on transcription. Required for the maintenance of emryonic stem cell identity and the reacquisition of pluripotency in somatic cells. May play an essential role in germ cell development at 2 levels: the reacquisition of potential pluripotency, including SOX2 up-regulation, and successful epigenetic reprogramming, characterized by EHMT1 repression (By similarity). Directly up-regulates the expression of pluripotency gene POU5F1 through its proximal enhancer. Binds to the DNA consensus sequence 5'-GGTC[TC]CTAA-3'. [UniProt] |
| 预测分子量 | 64 kDa |
检测图片 (2)
ARG56309 anti-PRDM14 antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human kidney stained with ARG56309 anti-PRDM14 antibody at 1:100 dilution.
ARG56309 anti-PRDM14 antibody WB image
Western blot: HeLa cell lysate stained with ARG56309 anti-PRDM14 antibody.
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