anti-PRELP antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG59712
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRELP |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRELP |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide between aa. 257-286 of Human PRELP. |
| 偶联标记 | Un-conjugated |
| 別名 | MST161; SLRR2A; Prolargin; Proline-arginine-rich end leucine-rich repeat protein; MSTP161 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | Y79 | ||||||||
| 实际分子量 | 43 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Saturated Ammonium Sulfate precipitation followed by dialysis against PBS. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PRELP |
| 全名 | proline/arginine-rich end leucine-rich repeat protein |
| 背景介绍 | The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008] |
| 生物功能 | May anchor basement membranes to the underlying connective tissue. [UniProt] |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. [UniProt] |
| 预测分子量 | 44 kDa |
检测图片 (3)
ARG59712 anti-PRELP antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human hepatocarcinoma stained with ARG59712 anti-PRELP antibody.
ARG59712 anti-PRELP antibody WB image
Western blot: 35 µg of Y79 cell lysate stained with ARG59712 anti-PRELP antibody.
ARG59712 anti-PRELP antibody FACS image
Flow Cytometry: WiDr cells stained with ARG59712 anti-PRELP antibody (bottom histogram) or without primary antibody as control (top histogram), followed by incubation with FITC-labelled secondary antibody.
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