anti-PRMT2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG59652
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PRMT2 |
|---|---|
| 反应物种 | Hu, Ms |
| 预测物种 | Cow, Rat, Dog, Gpig, Hrs, Pig, Rb |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PRMT2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around the N-terminal region of Human PRMT2. (within the following region: ESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILIL) |
| 偶联标记 | Un-conjugated |
| 別名 | EC 2.1.1.125; Histone-arginine N-methyltransferase PRMT2; HRMT1L1; Protein arginine N-methyltransferase 2; EC 2.1.1.- |
应用说明
| 预测反应性说明 | Predicted Homology Based On Immunogen Sequence: Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100% | ||||
|---|---|---|---|---|---|
| 应用建议 |
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| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS, 0.09% (w/v) Sodium azide and 2% Sucrose. |
| 抗菌剂 | 0.09% (w/v) Sodium azide |
| 稳定剂 | 2% Sucrose |
| 浓度 | Batch dependent: 0.5 - 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P55345 Human Protein arginine N-methyltransferase 2 |
|---|---|
| 基因名称 | PRMT2 |
| 全名 | protein arginine methyltransferase 2 |
| 生物功能 | Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1-dependent manner). May be involved in growth regulation. [UniProt] |
| 细胞定位 | Isoform 1: Cytoplasm. Nucleus. Note=Translocates from the cytoplasm to the nucleus, after hormone exposure. Excluded from nucleolus. Isoform PRMT2Alpha: Nucleus. Note=Excluded from nucleolus. Isoform PRMT2Beta: Cytoplasm. Nucleus. Nucleus, nucleolus. Isoform PRMT2Gamma: Nucleus. Note=Excluded from nucleolus. Isoform PRMT2L2: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. [UniProt] |
| 预测分子量 | 49 kDa |
检测图片 (2)
ARG59652 anti-PRMT2 antibody WB image
Western blot: Jurkat cell lysate stained with ARG59652 anti-PRMT2 antibody at 0.625 µg/ml dilution.
ARG59652 anti-PRMT2 antibody WB image
Western blot: Human LCL and Mouse brain lysates stained with ARG59652 anti-PRMT2 antibody at 1:1000 dilution.
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