anti-Prostaglandin E Receptor EP1 antibody
CAT.NO. : ARG55478
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes Prostaglandin E Receptor EP1 |
|---|---|
| 反应物种 | Ms |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | Prostaglandin E Receptor EP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human PTGER1 (NP_000946.2) |
| 偶联标记 | Un-conjugated |
| 別名 | PGE2 receptor EP1 subtype; Prostanoid EP1 receptor; PGE receptor EP1 subtype; Prostaglandin E2 receptor EP1 subtype; EP1 |
应用说明
| 预测反应性说明 | Mouse, Rat | ||||
|---|---|---|---|---|---|
| 应用建议 |
| ||||
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Romas | ||||
| 实际分子量 | 42 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P35375 Mouse Prostaglandin E2 receptor EP1 subtype |
|---|---|
| 基因名称 | PTGER1 |
| 全名 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| 背景介绍 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] |
| 生物功能 | Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 42 kDa |
| 翻译后修饰 | Phosphorylated. |
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