anti-PRPF8 antibody
CAT.NO. : ARG43978
US$ Please choose
US$ Please choose
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PRPF8 |
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反应物种 | Hu, Ms |
应用 | ELISA, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PRPF8 |
抗原物种 | Human |
抗原 | Human PRPF8 recombinant protein |
表达系统 | E.coli |
偶联标记 | Un-conjugated |
Protein Full name | Pre-mRNA-processing-splicing factor 8 |
別名 | PRPF8; Pre-MRNA Processing Factor 8; PRPC8; SNRNP220; Pre-MRNA-Processing-Splicing Factor 8; 220 KDa U5 SnRNP-Specific Protein; Splicing Factor Prp8; PRP8 Homolog; HPrp8; Prp8; RP13; P220; U5 SnRNP-Specific Protein (220 KD), Ortholog Of S. Cerevisiae Prp8p; PRP8 Pre-MRNA Processing Factor 8 Homolog; Precursor MRNA Processing Protein; Apoptosis-Regulated Protein; HPRP8; PRP8 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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缓冲液 | 0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose. |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
数据库连接 | Swiss-port # Q6P2Q9 Human Pre-mRNA-processing-splicing factor 8 Swiss-port # Q99PV0 Mouse Pre-mRNA-processing-splicing factor 8 |
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基因名称 | PRPF8 |
全名 | Pre-MRNA Processing Factor 8 |
背景介绍 | Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. |
生物功能 | Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. |
细胞定位 | Nucleus, Spliceosome |
预测分子量 | 274 kDa |
翻译后修饰 | Acetylation, Methylation, Phosphoprotein |
