anti-PRPF8 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PRPF8
  • 反应物种: Hu, Ms
  • 应用: ELISA, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PRPF8
  • 抗原物种: Human
  • 抗原: Human PRPF8 recombinant protein
  • Brand:
CAT.NO. : ARG43978
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PRPF8
反应物种Hu, Ms
应用ELISA, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PRPF8
抗原物种Human
抗原Human PRPF8 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full namePre-mRNA-processing-splicing factor 8
別名PRPF8; Pre-MRNA Processing Factor 8; PRPC8; SNRNP220; Pre-MRNA-Processing-Splicing Factor 8; 220 KDa U5 SnRNP-Specific Protein; Splicing Factor Prp8; PRP8 Homolog; HPrp8; Prp8; RP13; P220; U5 SnRNP-Specific Protein (220 KD), Ortholog Of S. Cerevisiae Prp8p; PRP8 Pre-MRNA Processing Factor 8 Homolog; Precursor MRNA Processing Protein; Apoptosis-Regulated Protein; HPRP8; PRP8
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 10594 Human PRPF8

GeneID: 192159 Mouse PRPF8

Swiss-port # Q6P2Q9 Human Pre-mRNA-processing-splicing factor 8

Swiss-port # Q99PV0 Mouse Pre-mRNA-processing-splicing factor 8

基因名称PRPF8
全名Pre-MRNA Processing Factor 8
背景介绍Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
生物功能Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome.
细胞定位Nucleus, Spliceosome
预测分子量274 kDa
翻译后修饰Acetylation, Methylation, Phosphoprotein
检测图片 (2)
  • ARG43978 anti-PRPF8 antibody WB image

    Western blot: Hela and SH-SY5Y stained with ARG43978anti-PRPF8 antibody at 0.5 μg/mL dilution.

  • ARG43978 anti-PRPF8 antibody WB image

    Western blot: NIH/3T3 stained with ARG43978anti-PRPF8 antibody at 0.5 μg/mL dilution.

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