anti-PRRT1 antibody
CAT.NO. : ARG44079
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概述
产品描述 | Rabbit Polyclonal recognizes PRRT1 |
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反应物种 | Hu, Ms, Rat |
应用 | FACS, ICC/IF, IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PRRT1 |
抗原物种 | Human |
抗原 | Human SynDIG4/PRRT1 recombinant protein (Position: M1-N270). |
偶联标记 | Un-conjugated |
別名 | PRRT1; Proline Rich Transmembrane Protein 1; DSPD1; NG5; Proline-Rich Transmembrane Protein 1; Dispanin Subfamily D Member 1; IFITMD7; C6orf31; Interferon Induced Transmembrane Protein Domain Containing 7; Synapse Differentiation-Induced Protein 4; SynDIG4; Chromosome 6 Open Reading Frame 31 |
应用说明
应用建议 |
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应用说明 | The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 4% Trehalose |
浓度 | 0.5 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | PRRT1 |
全名 | Proline Rich Transmembrane Protein 1 |
背景介绍 | Enables identical protein binding activity. Predicted to be involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA receptor activity. Predicted to act upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Predicted to be located in postsynaptic density membrane and synaptic vesicle membrane. Predicted to be active in glutamatergic synapse and membrane. Predicted to be integral component of postsynaptic membrane. |
生物功能 | Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression. |
细胞定位 | Cell membrane, Membrane, Synapse |
预测分子量 | 31 kDa |
检测图片 (5)
ARG44079 anti-PRRT1 antibody ICC/IF image
Immunofluorescence: U2OS stained with ARG44079 anti-PRRT1 antibody at 5 μg/ml dilution.
ARG44079 anti-PRRT1 antibody FACS image
Flow Cytometry: SH-SY5Y stained with ARG44079 anti-PRRT1 antibody at 1 µg/10^6 cells dilution.
ARG44079 anti-PRRT1 antibody WB image
Western blot: Rat brain stained with ARG44079 anti-PRRT1 antibody at 0.5 μg/mL dilution.
ARG44079 anti-PRRT1 antibody IHC-P image
Immunohistochemistry: Mouse brain stained with ARG44079 anti-PRRT1 antibody at 2 μg/ml dilution.
ARG44079 anti-PRRT1 antibody WB image
Western blot: Mouse brain stained with ARG44079 anti-PRRT1 antibody at 0.5 μg/mL dilution.
