anti-PRUNE2 / BMCC1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes PRUNE2 / BMCC1
  • 反应物种: Hu
  • 预测物种: Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PRUNE2 / BMCC1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64568
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes PRUNE2 / BMCC1
反应物种Hu
预测物种Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称PRUNE2 / BMCC1
抗原物种Human
抗原C-MESEKISEKQEE
偶联标记Un-conjugated
別名KIAA0367; Protein prune homolog 2; C9orf65; BNIPXL; BMCC1; BNIP2 motif-containing molecule at the C-terminal region 1
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 158471 Human PRUNE2

Swiss-port # Q8WUY3 Human Protein prune homolog 2

基因名称PRUNE2
全名prune homolog 2 (Drosophila)
背景介绍The protein encoded by this gene belongs to the B-cell CLL/lymphoma 2 and adenovirus E1B 19 kDa interacting family, whose members play roles in many cellular processes including apotosis, cell transformation, and synaptic function. Several functions for this protein have been demonstrated including suppression of Ras homolog family member A activity, which results in reduced stress fiber formation and suppression of oncogenic cellular transformation. A high molecular weight isoform of this protein has also been shown to colocalize with Adaptor protein complex 2, beta-Adaptin and endodermal markers, suggesting an involvement in post-endocytic trafficking. In prostate cancer cells, this gene acts as a tumor suppressor and its expression is regulated by prostate cancer antigen 3, a non-protein coding gene on the opposite DNA strand in an intron of this gene. Prostate cancer antigen 3 regulates levels of this gene through formation of a double-stranded RNA that undergoes adenosine deaminase actin on RNA-dependent adenosine-to-inosine RNA editing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
生物功能May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. [UniProt]
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量341 kDa
检测图片 (1)
  • ARG64568 anti-PRUNE2 / BMCC1 antibody WB image

    Western Blot: Human Brain lysate (35 µg protein in RIPA buffer) stained with ARG64568 anti-PRUNE2 / BMCC1 antibody at 1 µg/ml dilution.

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