anti-PSIP1 / LEDGF antibody
产品描述 | Mouse Monoclonal antibody recognizes PSIP1 / LEDGF |
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反应物种 | Hu, Ms, Rat, Mk |
应用 | ELISA, ICC/IF, IHC-P, WB |
宿主 | Mouse |
克隆 | Monoclonal |
靶点名称 | PSIP1 / LEDGF |
抗原物种 | Human |
抗原 | Human PSIP1 / LEDGF recombinant fragment |
偶联标记 | Un-conjugated |
別名 | PSIP1; PC4 And SRSF1 Interacting Protein 1; LEDGF; DFS70; Lens Epithelium-Derived Growth Factor; PSIP2; P52; P75; PC4 And SFRS1 Interacting Protein 1; Dense Fine Speckles 70 KDa Protein; PC4 And SFRS1-Interacting Protein; CLL-Associated Antigen KW-7; PC4 And SFRS1 Interacting Protein 2; Transcriptional Coactivator P52/P75; Transcriptional Coactivator P75/P52; DFS 70; PAIP |
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.5% BSA. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol and 0.5% BSA |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
数据库连接 | |
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基因名称 | PSIP1 |
全名 | PC4 And SRSF1 Interacting Protein 1 |
背景介绍 | Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear periphery; and nucleoplasm. |
生物功能 | Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. |
细胞定位 | Nucleus |
预测分子量 | 60 kDa |
翻译后修饰 | Citrullination; Isopeptide bond; Phosphoprotein; Ubl conjugation |
ARG67103 anti-PSIP1 / LEDGF antibody IHC-P image
Immunohistochemistry: Human breast cancer stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody WB image
Western blot: HepG2 and Jurkat stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody ICC/IF image
Immunofluorescence: NIH/3T3 stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody IHC-P image
Immunohistochemistry: Human ovarian cancer stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody WB image
Western blot: PC-12 stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody WB image
Western blot: NIH/3T3 stained with ARG67103 anti-PSIP1 / LEDGF antibody.
ARG67103 anti-PSIP1 / LEDGF antibody WB image
Western blot: Cos7 stained with ARG67103 anti-PSIP1 / LEDGF antibody.
