anti-PSMA5 / Proteasome 19S S5A antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG40957
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes PSMA5 / Proteasome 19S S5A |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 预测物种 | Bov |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 426CT8.5.1 |
| 同位型 | IgG1 |
| 靶点名称 | PSMA5 / Proteasome 19S S5A |
| 抗原物种 | Human |
| 抗原 | Purified His-tagged PSMA5 protein (fragment). |
| 偶联标记 | Un-conjugated |
| 別名 | Proteasome subunit alpha type-5; Macropain zeta chain; PSC5; Multicatalytic endopeptidase complex zeta chain; EC 3.4.25.1; ZETA; Proteasome zeta chain |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | K562 | ||||||||
| 实际分子量 | 26 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein G. |
| 缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
| 抗菌剂 | 0.09% (W/V) Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | PSMA5 |
| 全名 | proteasome subunit alpha 5 |
| 背景介绍 | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
| 生物功能 | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. [UniProt] |
| 细胞定位 | Cytoplasm. Nucleus. [UniProt] |
| 预测分子量 | 26 kDa |
检测图片 (3)
ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody ICC/IF image
Immunofluorescence: HeLa cells stained with ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody (green) at 1:25 dilution. Cytoplasmic actin was counterstained with Alexa Fluor® 555 conjugated with Phalloidin (red).
ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human testis tissue stained with ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody at 1:25 dilution.
ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody WB image
Western blot: 35 µg of K562 cell lysate stained with ARG40957 anti-PSMA5 / Proteasome 19S S5A antibody.
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