anti-PSMB2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PSMB2
  • 反应物种: Hu
  • 应用: ELISA, FACS, ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PSMB2
  • 抗原物种: Human
  • 抗原: Human PSMB2 recombinant protein
  • Brand:
CAT.NO. : ARG43991
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PSMB2
反应物种Hu
应用ELISA, FACS, ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PSMB2
抗原物种Human
抗原Human PSMB2 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameProteasome subunit beta type-2
別名PSMB2; Macropain subunit C7-I; Proteasome subunit beta type-2; Multicatalytic endopeptidase complex subunit C7-I; HC7-I; Proteasome component C7-I; EC 3.4.25.1
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
FACS1-3 µg/1x10^6
ICC/IF5 µg/ml
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 5690 Human PSMB2

Swiss-port # P49721 Human Proteasome subunit beta type-2

基因名称PSMB2
全名Proteasome 20S Subunit Beta 2
背景介绍The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
生物功能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity. [UniProt]
细胞定位Cytoplasm, Nucleus, Proteasome
预测分子量23 kDa
翻译后修饰Acetylation
检测图片 (3)
  • ARG43991 anti-PSMB2 antibody ICC/IF image

    Immunofluorescence:U2OS cells stained with ARG43991anti-PSMB2 antibody at 5 μg/ml dilution.

  • ARG43991 anti-PSMB2 antibody WB image

    Western blot: 293T and HeLa stained with ARG43991 anti-PSMB2 antibody at 0.5 μg/mL dilution.

  • ARG43991 anti-PSMB2 antibody FACS image

    Flow Cytometry: Raji cells stained with ARG43991anti-PSMB2 antibody (blue) at 1 μg/1x10^6 cells dilution.

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