anti-PSMD13 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PSMD13
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Chk
  • 应用: FACS, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PSMD13
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56225
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PSMD13
反应物种Hu
预测物种Ms, Rat, Chk
应用FACS, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PSMD13
抗原物种Human
抗原KLH-conjugated synthetic peptide corresponding to aa. 269-298 (C-terminal) of HHuman PSMD13.
偶联标记Un-conjugated
別名26S proteasome regulatory subunit RPN9; HSPC027; 26S proteasome non-ATPase regulatory subunit 13; Rpn9; S11; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit p40.5; p40.5
应用说明
应用建议
应用推荐稀释比
FACS1:10 - 1:50
IHC-P1:50 - 1:100
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Y79
属性
形式Liquid
纯化Purification with Protein A and immunogen peptide
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide.
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5719 Human PSMD13

Swiss-port # Q9UNM6 Human 26S proteasome non-ATPase regulatory subunit 13

基因名称PSMD13
全名proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
背景介绍The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
生物功能Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [UniProt]
预测分子量43 kDa
检测图片 (3)
  • ARG56225 anti-PSMD13 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human lung carcinoma tissue stained with ARG56225 anti-PSMD13 antibody.

  • ARG56225 anti-PSMD13 antibody WB image

    Western blot: 35 µg of Y79 cell lysate stained with ARG56225 anti-PSMD13 antibody.

  • ARG56225 anti-PSMD13 antibody FACS image

    Flow Cytometry: 293 cells stained with ARG56225 anti-PSMD13 antibody (bottom histogram) or without primary antibody control (top histogram), followed by incubation with FITC labelled secondary antibody.

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