anti-PSMD3 antibody
CAT.NO. : ARG66455
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PSMD3 |
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反应物种 | Hu, Ms, Rat |
预测物种 | Bov, Mk |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PSMD3 |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide within the center region of Human PSMD3. |
偶联标记 | Un-conjugated |
別名 | Proteasome subunit p58; RPN3; S3; TSTA2; 26S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; 26S proteasome non-ATPase regulatory subunit 3; P58 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | 0.42% Potassium phosphate (pH 7.3), 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 30% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O43242 Human 26S proteasome non-ATPase regulatory subunit 3 Swiss-port # P14685 Mouse 26S proteasome non-ATPase regulatory subunit 3 |
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基因名称 | PSMD3 |
全名 | proteasome 26S subunit, non-ATPase 3 |
背景介绍 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count. [provided by RefSeq, Jul 2012] |
生物功能 | Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. [UniProt] |
预测分子量 | 61 kDa |
