anti-PSMF1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes PSMF1
  • 反应物种: Hu
  • 应用: ELISA, FACS, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PSMF1
  • 抗原物种: Human
  • 抗原: Human PSMF1 recombinant protein
  • Brand:
CAT.NO. : ARG44002
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes PSMF1
反应物种Hu
应用ELISA, FACS, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PSMF1
抗原物种Human
抗原Human PSMF1 recombinant protein
表达系统E.coli
偶联标记Un-conjugated
Protein Full nameProteasome inhibitor PI31 subunit
別名PSMF1; Proteasome Inhibitor Subunit 1; PI31; Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31); Proteasome Inhibitor PI31 Subunit; Proteasome Inhibitor HP131 Subunit; HPI31
应用说明
应用建议
应用推荐稀释比
ELISA0.1-0.5 µg/ml
FACS1-3 µg/1x10^6
WB0.25-0.5 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液0.9% NaCl, 0.2% Na2HPO4 and 4% Trehalose.
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 9491 Human PSMF1

Swiss-port # Q92530 Human Proteasome inhibitor PI31 subunit

基因名称PSMF1
全名Proteasome Inhibitor Subunit 1
背景介绍The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
生物功能Plays an important role in control of proteasome function. Inhibits the hydrolysis of protein and peptide substrates by the 20S proteasome. Also inhibits the activation of the proteasome by the proteasome regulatory proteins PA700 and PA28.
细胞定位Cytoplasm, Endoplasmic reticulum, Proteasome
预测分子量30 kDa
翻译后修饰Acetylation, Methylation, Phosphoprotein
检测图片 (2)
  • ARG44002 anti-PSMF1 antibody WB image

    Western blot: Jurkat and HepG2 stained with ARG44002anti-PSMF1 antibody at 0.5 μg/mL dilution.

  • ARG44002 anti-PSMF1 antibody FACS image

    Flow Cytometry: JK cells stained with ARG44002 anti-PSMF1 antibody (blue) at 1 μg/1x10^6 cells dilution.

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