anti-PTH2R antibody

Key features and details

  • 产品描述: Rabbit Polyclonal recognizes PTH2R
  • 反应物种: Hu
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: PTH2R
  • 抗原物种: Human
  • 抗原: Human PTH2R recombinant protein (Position: A22-E511).
  • Brand:
CAT.NO. : ARG44093
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Product Details
概述
产品描述Rabbit Polyclonal recognizes PTH2R
反应物种Hu
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称PTH2R
抗原物种Human
抗原Human PTH2R recombinant protein (Position: A22-E511).
偶联标记Un-conjugated
別名PTH2R; Parathyroid Hormone 2 Receptor 2; PTHR2; Parathyroid Hormone Receptor 2; PTH2 Receptor
应用说明
应用建议
应用推荐稀释比
ICC/IF5 µg/ml
WB0.25 - 0.5 µg/ml
应用说明The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.9% NaCl, 0.2% Na2HPO4, 0.05% Sodium azide and 4% Trehalose.
抗菌剂0.05% Sodium azide
稳定剂4% Trehalose
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5746 Human PTH2R

Swiss-port # P49190 Human Parathyroid hormone 2 receptor

基因名称PTH2R
全名Parathyroid Hormone 2 Receptor
背景介绍The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.
生物功能This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.
细胞定位Cell membrane, Membrane
预测分子量62 kDa
翻译后修饰Glycoprotein
检测图片 (2)
  • ARG44093 anti-PTH2R antibody ICC/IF image

    Immunofluorescence: U2OS stained with ARG44093 anti-PTH2R antibody at 5 μg/ml dilution.

  • ARG44093 anti-PTH2R antibody WB image

    Western blot: HEL and SH-SY5Y stained with ARG44093 anti-PTH2R antibody at 0.5 μg/mL dilution.

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