anti-PTPN3 / PTPH1 antibody
CAT.NO. : ARG57283
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概述
产品描述 | Rabbit Polyclonal antibody recognizes PTPN3 / PTPH1 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | PTPN3 / PTPH1 |
抗原物种 | Human |
抗原 | Recombinant protein of Human PTPN3 / PTPH1. |
偶联标记 | Un-conjugated |
別名 | PTPH1; EC 3.1.3.48; Protein-tyrosine phosphatase H1; Tyrosine-protein phosphatase non-receptor type 3; PTP-H1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | BT474 |
属性
形式 | Liquid |
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纯化 | Affinity purification with immunogen. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # A2ALK8 Mouse Tyrosine-protein phosphatase non-receptor type 3 Swiss-port # P26045 Human Tyrosine-protein phosphatase non-receptor type 3 |
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基因名称 | PTPN3 |
全名 | protein tyrosine phosphatase, non-receptor type 3 |
背景介绍 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009] |
生物功能 | May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. [UniProt] |
预测分子量 | 104 kDa |
