anti-PWP1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG42878
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes PWP1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | FACS, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | PWP1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human PWP1. |
| 偶联标记 | Un-conjugated |
| 別名 | Periodic tryptophan protein 1 homolog; IEF-SSP-9502; Keratinocyte protein IEF SSP 9502 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | K562 | ||||||
| 实际分子量 | 72 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 40% Glycerol and 0.05% BSA |
| 浓度 | Batch dependent |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q13610 Human Periodic tryptophan protein 1 homolog Swiss-port # Q99LL5 Mouse Periodic tryptophan protein 1 homolog |
|---|---|
| 基因名称 | PWP1 |
| 全名 | PWP1 homolog, endonuclein |
| 背景介绍 | The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
| 生物功能 | Chromatin-associated factor that regulates transcription (PubMed:29065309). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309). Regulates the epigenetic status of rDNA (PubMed:29065309). [UniProt] |
| 细胞定位 | Nucleus. [UniProt] |
| 预测分子量 | 56 kDa |
检测图片 (1)
ARG42878 anti-PWP1 antibody WB image
Western blot: K562 cell lysate stained with ARG42878 anti-PWP1 antibody at 1:1000 dilution.
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