anti-QPRT antibody [24C4]
![anti-QPRT antibody [24C4]](/upload/image/products/ARG57068_WB_1_210_205.jpg)
![anti-QPRT antibody [24C4]](/upload/image/products/ARG57068_WB_1.jpg)
Key features and details
- 产品描述:
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- 克隆:
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- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57068
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [24C4] recognizes QPRT |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | 24C4 |
| 同位型 | IgG2a, kappa |
| 靶点名称 | QPRT |
| 抗原物种 | Human |
| 抗原 | Recombinant fragment around aa. 1-297 of Human QPRT. |
| 偶联标记 | Un-conjugated |
| 別名 | QAPRTase; QPRTase; Quinolinate phosphoribosyltransferase [decarboxylating]; HEL-S-90n; Nicotinate-nucleotide pyrophosphorylase [carboxylating]; EC 2.4.2.19 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 10% Glycerol |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q15274 Human Nicotinate-nucleotide pyrophosphorylase [carboxylating] |
|---|---|
| 基因名称 | QPRT |
| 全名 | quinolinate phosphoribosyltransferase |
| 背景介绍 | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq, Jul 2008] |
| 生物功能 | Involved in the catabolism of quinolinic acid (QA). [UniProt] |
| 预测分子量 | 31 kDa |
检测图片 (1)
ARG57068 anti-QPRT antibody [24C4] WB image
Western blot: 40 µg of 1) HepG2 cell lysate, 2) K562 cell lysate stained with ARG57068 anti-QPRT antibody [24C4] at 1:1000.
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