anti-RAB11A / YL8 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes RAB11A / YL8
  • 反应物种: Hu, Ms, Rat
  • 预测物种: Chk, Dog, Sheep
  • 应用: IHC-P, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 1565CT164.36.80
  • 同位型: IgG1, kappa
  • 靶点名称: RAB11A / YL8
  • Brand:
CAT.NO. : ARG55646
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述Mouse Monoclonal antibody recognizes RAB11A / YL8
反应物种Hu, Ms, Rat
预测物种Chk, Dog, Sheep
应用IHC-P, WB
宿主Mouse
克隆Monoclonal
克隆号1565CT164.36.80
同位型IgG1, kappa
靶点名称RAB11A / YL8
抗原物种Human
抗原Recombinant protein corresponding to aa. 1-216 of Human RAB11A.
偶联标记Un-conjugated
別名Rab-11; Ras-related protein Rab-11A; YL8
应用说明
应用建议
应用推荐稀释比
IHC-P1:25
WB1:4000
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HeLa
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% (W/V) Sodium azide.
抗菌剂0.09% (W/V) Sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 53869 Mouse RAB11A

GeneID: 81830 Rat RAB11A

GeneID: 8766 Human RAB11A

基因名称RAB11A
全名RAB11A, member RAS oncogene family
背景介绍The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
生物功能The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes. May also play a role in melanosome transport and release from melanocytes. [UniProt]
预测分子量24 kDa
检测图片 (2)
  • ARG55646 anti-RAB11A / YL8 antibody IHC-P image

    Immunohistochemistry: Paraformaldehyde-fixed and paraffin-embedded Human brain tissue stained with ARG55646 anti-RAB11A / YL8 antibody at 1:25 dilution for 1 hour at 37°C. Tissue was blocked with 3% BSA for 0.5 hour at room temperature. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0).

  • ARG55646 anti-RAB11A / YL8 antibody WB image

    Western blot: 20 µg of HeLa whole cell lysate stained with ARG55646 anti-RAB11A / YL8 antibody at 1:4000 dilution.

New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap