anti-Rabphilin 3A phospho (Ser234) antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes Rabphilin 3A phospho (Ser234)
  • 反应物种: Rat
  • 预测物种: Ms
  • 应用: IHC, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Rabphilin 3A
  • 抗原物种: Rat
  • Brand:
CAT.NO. : ARG52408
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes Rabphilin 3A phospho (Ser234)
反应物种Rat
预测物种Ms
应用IHC, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称Rabphilin 3A
抗原物种Rat
抗原Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser234 conjugated to KLH
偶联标记Un-conjugated
別名Rabphilin-3A; Exophilin-1
应用说明
应用建议
应用推荐稀释比
IHC1:400
WB1:1000
应用说明Specific for the ~82k rabphilin protein phosphorylated at Ser234. The immunolabeling of the rabphilin band was completely blocked by the phosphopeptide used as antigen while the dephosphopeptide had no effect on the immunolabeling
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity Purified
缓冲液10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
稳定剂0.1 mg/ml BSA, 50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 171039 Rat RPH3A

Swiss-port # P47709 Rat Rabphilin-3A

基因名称RPH3A
全名rabphilin 3A
背景介绍Rabphilin-3A is a peripheral membrane protein that binds Ca2+ and phospholipids and is attached to synaptic vesicle membranes (Geppert et al., 1994;Li et al., 1994). The expression of rabphilin 3A is reduced in an animal model of Huntington’s disease(Smith et al., 2005). Rabphilin can be phosphorylated at Ser234 by both CAM kinase II and PKA and this phosphorylation has been suggested to regulate neuronal activity during development in a synapse-specific manner (Fykse et al., 1995;Foletti and Scheller, 2001).
研究领域Neuroscience antibody
预测分子量77 kDa
检测图片 (2)
  • ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody WB image

    Western blot: Rat brain lysate showing specific immunolabeling of the ~82k rabphilin 3A phosphorylated at Ser 234 stained with ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody.

  • ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody IHC image

    Immunohistochemistry: 14 DIV Rat cortical neurons showing Rabphilin 3A when phosphorylated at Ser234 stained with ARG52408 anti-Rabphilin 3A phospho (Ser234) antibody in red and PSD95 in green.

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