anti-RANBP8 / IPO8 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes RANBP8 / IPO8
  • 反应物种: Hu
  • 预测物种: Cow, Dog, Pig
  • 应用: IHC-P
  • 特异性: This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RANBP8 / IPO8
  • Brand:
CAT.NO. : ARG63366
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes RANBP8 / IPO8
反应物种Hu
预测物种Cow, Dog, Pig
应用IHC-P
特异性This antibody is expected to recognise isoform 1 (NP_006381.2) and isoform 2 (NP_001177924.1).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称RANBP8 / IPO8
抗原物种Human
抗原C-SAFNFGTVPSNN
偶联标记Un-conjugated
別名Imp8; Importin-8; Ran-binding protein 8; RANBP8; RanBP8
应用说明
应用建议
应用推荐稀释比
IHC-P4 - 6 µg/ml
应用说明IHC-P: Antigen Retrieval: Steam tissue section in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10526 Human IPO8

Swiss-port # O15397 Human Importin-8

背景介绍The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
研究领域Gene Regulation antibody; Signaling Transduction antibody
预测分子量120 kDa
检测图片 (1)
  • ARG63366 anti-RANBP8 / IPO8 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Tonsil. (Steamed antigen retrieval with Tris/EDTA buffer pH 9) stained with ARG63366 anti-RANBP8 / IPO8 antibody at 4 µg/ml dilution followed by HRP-staining. Similar results were obtained after antigen retrieval at pH9.

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