anti-RAPSN / Rapsyn antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes RAPSN / Rapsyn
  • 反应物种: Hu
  • 预测物种: Ms, Rat
  • 应用: WB
  • 特异性: This antibody is expected to recognize both reported isoforms (NP_005046.2; NP_116034.2).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RAPSN / Rapsyn
  • Brand:
CAT.NO. : ARG64986
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes RAPSN / Rapsyn
反应物种Hu
预测物种Ms, Rat
应用WB
特异性This antibody is expected to recognize both reported isoforms (NP_005046.2; NP_116034.2).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称RAPSN / Rapsyn
抗原物种Human
抗原YQSNQTEKALQVWTK-C
偶联标记Un-conjugated
別名FADS; RING finger protein 205; 43 kDa receptor-associated protein of the synapse; Acetylcholine receptor-associated 43 kDa protein; CMS11; 43 kDa postsynaptic protein; RNF205; CMS4C; RAPsyn; RAPSYN
应用说明
应用建议
应用推荐稀释比
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 5913 Human RAPSN

Swiss-port # Q13702 Human 43 kDa receptor-associated protein of the synapse

背景介绍This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]
研究领域Neuroscience antibody
预测分子量46 kDa
翻译后修饰Ubiquitinated by the BCR(KLHL8) complex, leading to its degradation.
检测图片 (1)
  • ARG64986 anti-RAPSN / Rapsyn antibody WB image

    Western Blot: Human Skeletal Muscle lysate (35 µg protein in RIPA buffer) stained with ARG64986 anti-RAPSN / Rapsyn antibody at 0.5 µg/ml dilution.

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