anti-RASSF2 antibody
CAT.NO. : ARG42860
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概述
产品描述 | Rabbit Polyclonal antibody recognizes RASSF2 |
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反应物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | RASSF2 |
抗原物种 | Human |
抗原 | Synthetic peptide of Human RASSF2. |
偶联标记 | Un-conjugated |
別名 | CENP-34; Ras association domain-containing protein 2; RASFADIN |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | HeLa | ||||
实际分子量 | ~ 39 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05% BSA |
浓度 | Batch dependent |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # P50749 Human Ras association domain-containing protein 2 |
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基因名称 | RASSF2 |
全名 | Ras association (RalGDS/AF-6) domain family member 2 |
背景介绍 | This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008] |
生物功能 | Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation. [UniProt] |
细胞定位 | Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1. [UniProt] |
预测分子量 | 38 kDa |
翻译后修饰 | Phosphorylated by STK3/MST2 and STK4/MST1. [UniProt] |
