anti-RHBDD1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes RHBDD1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: RHBDD1
  • 抗原物种: Human
  • 抗原: Recombinant fusion protein corresponding to aa. 206-315 of Human RHBDD1 (NP_115652.2).
  • Brand:
CAT.NO. : ARG40080
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes RHBDD1
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称RHBDD1
抗原物种Human
抗原Recombinant fusion protein corresponding to aa. 206-315 of Human RHBDD1 (NP_115652.2).
偶联标记Un-conjugated
別名EC 3.4.21.105; RRP4; Rhomboid-related protein 4; Rhomboid-like protein 4; Rhomboid domain-containing protein 1
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat brain, Mouse brain and Raji
实际分子量38 kDa
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 316557 Rat RHBDD1

GeneID: 76867 Mouse RHBDD1

GeneID: 84236 Human RHBDD1

基因名称RHBDD1
全名rhomboid domain containing 1
生物功能Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia. [UniProt]
细胞定位Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion. [UniProt]
预测分子量36 kDa
检测图片 (1)
  • ARG40080 anti-RHBDD1 antibody WB image

    Western blot: 25 µg of Rat brain, Mouse brain and Raji cell lysates stained with ARG40080 anti-RHBDD1 antibody at 1:1000 dilution.

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