anti-RNASE1 / Ribonuclease A antibody
CAT.NO. : ARG59084
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概述
产品描述 | Rabbit Polyclonal antibody recognizes RNASE1 / Ribonuclease A |
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反应物种 | Ms |
预测物种 | Hu |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | RNASE1 / Ribonuclease A |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 29-156 of Human RNASE1 / Ribonuclease A (NP_937875.1). |
偶联标记 | Un-conjugated |
別名 | Ribonuclease A; RNase A; RNS1; RAC1; RIB1; EC 3.1.27.5; Ribonuclease 1; RNase 1; Ribonuclease pancreatic; RNase UpI-1; RIB-1; HP-RNase |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse pancreas | ||||
实际分子量 | 15kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | RNASE1 |
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全名 | ribonuclease, RNase A family, 1 (pancreatic) |
背景介绍 | This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
生物功能 | Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA. [UniProt] |
细胞定位 | Secreted. [UniProt] |
预测分子量 | 18 kDa |
翻译后修饰 | N-linked glycans are of complex type. [UniProt] |
