anti-RNASEH2B antibody [RM433]
![anti-RNASEH2B antibody [RM433]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 克隆号:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG45047
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Product Details
概述
| 产品描述 | Rabbit monoclonal [RM433] recognizes RNASEH2B. |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P, WB |
| 特异性 | This antibody reacts to human RNASEH2B |
| 宿主 | Rabbit |
| 克隆 | Monoclonal |
| 克隆号 | RM433 |
| 同位型 | IgG |
| 靶点名称 | RNASEH2B |
| 抗原 | A peptide corresponding to the C-terminus of RNASEH2B |
| 偶联标记 | Un-conjugated |
| 別名 | RNASEH2B; Ribonuclease H2 Subunit B; Deleted In Lymphocytic Leukemia 8; DLEU8; AGS2; Aicardi-Goutieres Syndrome 2 Protein; Ribonuclease HI Subunit B; RNase H2 Subunit B; FLJ11712; Aicardi-Goutieres Syndrome 2; Ribonuclease H2, Subunit B |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A. |
| 缓冲液 | PBS with 50% Glycerol, 1% BSA and 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 稳定剂 | 50% Glycerol, 1% BSA and 0.09% |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RNASEH2B |
| 全名 | Ribonuclease H2 Subunit B |
| 背景介绍 | RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008] |
| 生物功能 | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. [Uniprot] |
| 翻译后修饰 | Acetylation, Phosphoprotein. [Uniprot] |
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