anti-RNF135 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原表位:
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Brand:
CAT.NO. : ARG44918
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody recognizes RNF135 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG1 |
| 靶点名称 | RNF135 |
| 抗原物种 | Human |
| 抗原表位 | HLRKNTLLQD LADKYRRAAR EIQAGSDPAH CPCPGSSSLS SAAARPRRRP ELQRVAVEKS ITEVAQELTE LVEHLVDIVR SLQNQRPLSE SGPDNELSIL GKAFSSGVDL SMASPKLVTS DTAAGKIRDI LHDLEEIQEK LQESVTWKEA PEAQMQGELL |
| 偶联标记 | Un-conjugated |
| 別名 | RNF135; Ring Finger Protein 135; Riplet; RING Finger Protein Leading To RIG-I Activation; RING-Type E3 Ubiquitin Transferase RNF135; E3 Ubiquitin-Protein Ligase RNF135; RIG-I E3 Ubiquitin Ligase; MGC13061; REUL; RING Finger Protein 135; EC 2.3.2.27; MMFD; L13 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q8IUD6 Human E3 ubiquitin-protein ligase RNF135 |
|---|---|
| 基因名称 | RNF135 |
| 全名 | Ring Finger Protein 135 |
| 背景介绍 | The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| 生物功能 | This second mechanism that synergizes with the ubiquitin-dependent one would thereby allow an RNA length-dependent regulation of the RIG-I signaling pathway (Probable). Associated with the E2 ligase UBE2N, also constitutively synthesizes unanchored 'Lys-63'-linked polyubiquitin chains that may also activate the RIG-I signaling pathway. [UniProt] |
| 细胞定位 | Cytoplasm |
| 预测分子量 | 48 kDa |
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