anti-RPAIN antibody
CAT.NO. : ARG44924
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概述
| 产品描述 | Mouse Monoclonal antibody recognizes RPAIN |
|---|---|
| 反应物种 | Hu |
| 应用 | IHC-P |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2b |
| 靶点名称 | RPAIN |
| 抗原物种 | Human |
| 抗原表位 | LNRYRQAGSS GPGNSQNSFL VQEVMEEEWN ALQSVENCPE DLAQLEELID MAVLEEIQQE LINQEQSIIS EYEKSLQFDE |
| 偶联标记 | Un-conjugated |
| 別名 | RPAIN; RPA Interacting Protein; HRIP; RIP; RPA-Interacting Protein; MGC4189; RAP Interaction Protein; Nuclear Transporter |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | RPAIN |
| 全名 | RPA Interacting Protein |
| 背景介绍 | Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including DNA metabolic process; protein import into nucleus; and response to UV. Located in PML body; cytoplasm; and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism. [UniProt] |
| 细胞定位 | Cytoplasm, Nucleus. [UniProt] |
| 预测分子量 | 25 kDa |
| 翻译后修饰 | Isopeptide bond, Phosphoprotein, Ubl conjugation. [UniProt] |
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