anti-RRAS2 / TC21 antibody [EM-50]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [EM-50] recognizes RRAS2 / TC21
  • 反应物种: Hu
  • 应用: FACS, ICC/IF
  • 特异性: The antibody recognizes RRAS2 / TC21 protein and does not react with RRAS1, H-Ras, K-Ras, and N-Ras.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: EM-50
  • 同位型: IgG1
  • 靶点名称: RRAS2 / TC21
  • Brand:
CAT.NO. : ARG57574
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Product Details
概述
产品描述Mouse Monoclonal antibody [EM-50] recognizes RRAS2 / TC21
反应物种Hu
应用FACS, ICC/IF
特异性The antibody recognizes RRAS2 / TC21 protein and does not react with RRAS1, H-Ras, K-Ras, and N-Ras.
宿主Mouse
克隆Monoclonal
克隆号EM-50
同位型IgG1
靶点名称RRAS2 / TC21
抗原物种Human
抗原Human TC21.
偶联标记Un-conjugated
別名TC21; Teratocarcinoma oncogene; Ras-related protein R-Ras2; Ras-like protein TC21
应用说明
应用建议
应用推荐稀释比
FACS1 - 4 µg/ml
ICC/IFAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
纯度> 95% (by SDS-PAGE)
缓冲液PBS (pH 7.4) and 15 mM Sodium azide.
抗菌剂15mM Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 22800 Human RRAS2

Swiss-port # P62070 Human Ras-related protein R-Ras2

基因名称RRAS2
全名RRAS2
背景介绍This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010]
生物功能It is a plasma membrane-associated GTP-binding protein with GTPase activity. Might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins but in an antagonistic fashion. [UniProt]
预测分子量23 kDa
翻译后修饰May be post-translationally modified by both palmitoylation and polyisoprenylation. [UniProt]
检测图片 (2)
  • ARG57574 anti-RRAS2 / TC21 antibody [EM-50] ICC/IF image

    Immunofluorescence: Colocalization of RRAS2 / TC21 signal (red) and GFP signal (green) in COS cells transfected with RRAS2 / TC21-GFP construct, after fixation and permeabilization. RRAS2 / TC21 was detected using ARG57574 anti-RRAS2 / TC21 antibody [EM-50].

  • ARG57574 anti-RRAS2 / TC21 antibody [EM-50] FACS image

    Flow Cytometry: RRAS2-GFP transfected HEK293 cells stained with ARG57574 anti-RRAS2 / TC21 antibody [EM-50], followed by incubation with APC labelled Goat anti-Mouse secondary antibody.

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