anti-S100 antibody [D28-E]

Key features and details

  • 产品描述: Rabbit Monoclonal antibody [D28-E] recognizes S100
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: D28-E
  • 同位型: IgG
  • 靶点名称: S100
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG10589
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Product Details
概述
产品描述Rabbit Monoclonal antibody [D28-E] recognizes S100
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号D28-E
同位型IgG
靶点名称S100
抗原物种Human
抗原Synthetic peptide around the C-terminus of Human S100-A1 protein
偶联标记Un-conjugated
別名S-100 protein subunit alpha; S100 calcium-binding protein A1; S-100 protein alpha chain; S100-alpha; S100; Protein S100-A1; S100A
应用说明
应用建议
应用推荐稀释比
IHC-P1:100 - 1:200
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
缓冲液20 mM Tris-HCl (pH 8.0), 0.05% Sodium azide and 20 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂20 mg/ml BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6271 Human S100A1

Swiss-port # P23297 Human Protein S100-A1

基因名称S100A1
全名S100 calcium binding protein A1
背景介绍The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
生物功能Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. [UniProt]
预测分子量11 kDa
检测图片 (1)
  • ARG10589 anti-S100 antibody [D28-E] IHC-P image

    Immunohistochemistry: Formalin fixed, paraffin embedded Human cutaneous malignant melanoma (4 µm section) stained with ARG10589 anti-S100 antibody [D28-E].

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