anti-S100 antibody [D28-E]

CAT.NO. : ARG10589

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Size:

100 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Rabbit Monoclonal antibody [D28-E] recognizes S100
反应物种	Hu
应用	IHC-P
宿主	Rabbit
克隆	Monoclonal
克隆号	D28-E
同位型	IgG
靶点名称	S100
抗原物种	Human
抗原	Synthetic peptide around the C-terminus of Human S100-A1 protein
偶联标记	Un-conjugated
別名	S-100 protein subunit alpha; S100 calcium-binding protein A1; S-100 protein alpha chain; S100-alpha; S100; Protein S100-A1; S100A

应用说明

应用建议

应用	推荐稀释比
IHC-P	1:100 - 1:200

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
缓冲液	20 mM Tris-HCl (pH 8.0), 0.05% Sodium azide and 20 mg/ml BSA
抗菌剂	0.05% Sodium azide
稳定剂	20 mg/ml BSA
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 6271 Human S100A1 Swiss-port # P23297 Human Protein S100-A1
基因名称	S100A1
全名	S100 calcium binding protein A1
背景介绍	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]
生物功能	Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity. [UniProt]
预测分子量	11 kDa

检测图片 (1)

ARG10589 anti-S100 antibody [D28-E] IHC-P image
Immunohistochemistry: Formalin fixed, paraffin embedded Human cutaneous malignant melanoma (4 µm section) stained with ARG10589 anti-S100 antibody [D28-E].

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