anti-SAP102 antibody [S19-2]
CAT.NO. : ARG22262
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概述
产品描述 | Mouse Monoclonal antibody [S19-2] recognizes SAP102 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, IHC, IP, WB |
特异性 | Detects ~105kDa. No cross-reactivity against PSD95, SAP97 or Chapsyn-110. |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | S19-2 |
同位型 | IgG1 |
靶点名称 | SAP102 |
抗原物种 | Rat |
抗原 | Fusion protein around aa. 1-120 of Rat SAP102 |
偶联标记 | Un-conjugated |
別名 | MRX; SAP102; NEDLG; SAP-102; Neuroendocrine-DLG; Synapse-associated protein 102; MRX90; Disks large homolog 3; PPP1R82; XLMR |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol |
抗菌剂 | 0.09% Sodium azide |
稳定剂 | 50% Glycerol |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | Dlg3 |
全名 | discs, large homolog 3 (Drosophila) |
背景介绍 | This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009] |
生物功能 | Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. [UniProt] |
细胞定位 | Cytoplasm, Basolateral Cell Membrane, Cell Junction, growth cone, postsynaptic cell membrane, postsynaptic density, Synapse |
预测分子量 | 90 kDa |
检测图片 (2)
ARG22262 anti-SAP102 antibody [S19-2] ICC/IF image
Immunofluorescence: Human Neuroblastoma cell line SK-N-BE. Fixation: 4% Formaldehyde for 15 min at RT. Primary Antibody: ARG22262 anti-SAP102 antibody [S19-2] at 1:100 for 60 min at RT. Secondary Antibody: Goat anti-Mouse ATTO 488 at 1:100 for 60 min at RT. Counterstain: Phalloidin Texas Red F-Actin stain; DAPI (blue) nuclear stain. Magnification: 60X. (A) DAPI (blue) nuclear stain (B) Phalloidin Texas Red F-Actin stain (C) ARG22262 anti-SAP102 antibody [S19-2] (D) Composite.
ARG22262 anti-SAP102 antibody [S19-2] WB image
Western blot: Rat brain lysates stained with ARG22262 anti-SAP102 antibody [S19-2] at 1:1000 dilution.
