anti-SARM1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SARM1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SARM1
  • 抗原物种: Human
  • 抗原: Full length recombinant human SARM1 protein
  • Brand:
CAT.NO. : ARG44284
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SARM1
反应物种Hu, Ms, Rat
应用ICC/IF, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SARM1
抗原物种Human
抗原Full length recombinant human SARM1 protein
偶联标记Un-conjugated
別名SARM1; Sterile Alpha And TIR Motif Containing 1; SAMD2; SARM; KIAA0524; Sterile Alpha And TIR Motif-Containing Protein 1; Sterile Alpha Motif Domain-Containing Protein 2; Sterile Alpha And Armadillo Repeat Protein; SAM Domain-Containing Protein 2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Antigen Affinity Purified
缓冲液10 mM HEPES (pH 7.5), 150 mM NaCl, 50% Glycerol and 100 µg/ml BSA.
稳定剂50% Glycerol and 100 µg/ml BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
生物信息
数据库连接

GeneID: 23098 Human SARM1

GeneID: 237868 Mouse SARM1

Swiss-port # Q6PDS3 Mouse Sterile alpha and TIR motif-containing protein 1

Swiss-port # Q6SZW1 Human Sterile alpha and TIR motif-containing protein 1

基因名称SARM1
全名Sterile Alpha And TIR Motif Containing 1
背景介绍Enables NAD+ nucleotidase, cyclic ADP-ribose generating and identical protein binding activity. Involved in NAD catabolic process; positive regulation of neuron death; and response to axon injury. Located in mitochondrion.
生物功能Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
细胞定位Cell projection, Cytoplasm, Mitochondrion, Synapse
预测分子量79 kDa
翻译后修饰Phosphoprotein
检测图片 (2)
  • ARG44284 anti-SARM1 antibody ICC/IF image

    Immunofluorescence: COS-7 stained with ARG44284 anti-SARM1 antibody.

  • ARG44284 anti-SARM1 antibody WB image

    Western blot: HeLa stained with ARG44284 anti-SARM1 antibody.

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