anti-SARM1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG44284
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SARM1 |
|---|---|
| 反应物种 | Hu, Ms, Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SARM1 |
| 抗原物种 | Human |
| 抗原 | Full length recombinant human SARM1 protein |
| 偶联标记 | Un-conjugated |
| 別名 | SARM1; Sterile Alpha And TIR Motif Containing 1; SAMD2; SARM; KIAA0524; Sterile Alpha And TIR Motif-Containing Protein 1; Sterile Alpha Motif Domain-Containing Protein 2; Sterile Alpha And Armadillo Repeat Protein; SAM Domain-Containing Protein 2 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Antigen Affinity Purified |
| 缓冲液 | 10 mM HEPES (pH 7.5), 150 mM NaCl, 50% Glycerol and 100 µg/ml BSA. |
| 稳定剂 | 50% Glycerol and 100 µg/ml BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
生物信息
| 数据库连接 | Swiss-port # Q6PDS3 Mouse Sterile alpha and TIR motif-containing protein 1 Swiss-port # Q6SZW1 Human Sterile alpha and TIR motif-containing protein 1 |
|---|---|
| 基因名称 | SARM1 |
| 全名 | Sterile Alpha And TIR Motif Containing 1 |
| 背景介绍 | Enables NAD+ nucleotidase, cyclic ADP-ribose generating and identical protein binding activity. Involved in NAD catabolic process; positive regulation of neuron death; and response to axon injury. Located in mitochondrion. |
| 生物功能 | Involved in innate immune response: inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38. |
| 细胞定位 | Cell projection, Cytoplasm, Mitochondrion, Synapse |
| 预测分子量 | 79 kDa |
| 翻译后修饰 | Phosphoprotein |
检测图片 (2)
ARG44284 anti-SARM1 antibody ICC/IF image
Immunofluorescence: COS-7 stained with ARG44284 anti-SARM1 antibody.
ARG44284 anti-SARM1 antibody WB image
Western blot: HeLa stained with ARG44284 anti-SARM1 antibody.
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