Anti-SARS-CoV-2 Spike Protein Mouse Monoclonal Antibody (G5)
Key features and details
- Clone:
- Host:
- Species Reactivity:
- Application:
- Clone Type:
- Storage:
-
Brand:
CAT.NO. : AXA0001
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Size:
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Product Details
Background
The spike protein (S protein) of SARS-CoV-2 is a key structural protein on the surface of the novel coronavirus, responsible for recognizing the host cell receptor ACE2 and mediating the membrane fusion process. The S protein exists as a trimer, with each monomer containing approximately 1300 amino acids and consisting of two subunits, S1 and S2. The receptor-binding domain (RBD) of the S1 subunit is responsible for binding to ACE2, while the S2 subunit promotes membrane fusion through conformational changes.
Application
|
Application |
Recommended Dilution Ratio |
|
WB |
1:500-1:1000 |
|
IF |
1:500-1:1000 |
|
ELISA |
1:2000-1:10000 |
Overview
|
Host |
Mouse |
|
Clonality |
Monoclonal |
|
Applications |
WB (Western Blot), IF (Immunofluorescence), ELISA (Enzyme-Linked Immunosorbent Assay) |
|
Reactivity |
SARS-CoV-2 Spike Protein (S Protein) |
|
Appearance |
Liquid |
|
Storage Buffer |
PBS, 20% Glycerol; Preservative: 0.05% Sodium Azide |
|
Storage Conditions |
Store at -20°C, valid for 1 year. Avoid repeated freeze-thaw cycles. |
|
Concentration |
1 mg/ml |
|
Immunogen |
SARS-CoV-2 Spike Protein (S Protein) |
Data
ELISA results indicate that this antibody can effectively recognize the S2 antigen polypeptide.
WB and IFA results demonstrate that this antibody can effectively recognize the SARS-CoV-2 S protein expressed in 293T cells, and animal experiments have confirmed that this monoclonal antibody possesses therapeutic and preventive activities against SARS-CoV-2.
Storage
Store at -20°C. Stable for one year from the date of shipment.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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