anti-SBDS antibody [1E8]

CAT.NO. : ARG57006

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Size:

50 μl

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [1E8] recognizes SBDS
反应物种	Hu
应用	WB
宿主	Mouse
克隆	Monoclonal
克隆号	1E8
同位型	IgG2b, kappa
靶点名称	SBDS
抗原物种	Human
抗原	Recombinant fragment around aa. 1-250 of Human SBDS.
偶联标记	Un-conjugated
別名	Ribosome maturation protein SBDS; Shwachman-Bodian-Diamond syndrome protein; SWDS; CGI-97; SDS

应用说明

应用建议

应用	推荐稀释比
WB	1:3000

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein G.
缓冲液	PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂	0.02% Sodium azide
稳定剂	10% Glycerol
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 51119 Human SBDS Swiss-port # Q9Y3A5 Human Ribosome maturation protein SBDS
基因名称	SBDS
全名	Shwachman-Bodian-Diamond syndrome
背景介绍	This gene encodes a member of a highly conserved protein family that exists from archaea to vertebrates and plants. The encoded protein may function in RNA metabolism. Mutations within this gene are associated with Shwachman-Bodian-Diamond syndrome. An alternative transcript has been described, but its biological nature has not been determined. This gene has a closely linked pseudogene that is distally located. [provided by RefSeq, Jul 2008]
生物功能	Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation. [UniProt]
预测分子量	29 kDa

检测图片 (1)

ARG57006 anti-SBDS antibody [1E8] WB image
Western blot: 40 µg of 1) 293T cell lysate, 2) HeLa cell lysate stained with ARG57006 anti-SBDS antibody [1E8] at 1:3000.

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